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Target
Vitamin D3 receptor
Ligand
BDBM50329720
Substrate
n/a
Meas. Tech.
ChEMBL_674300 (CHEMBL1274500)
EC50
>30000±n/a nM
Citation
 Maruyama, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M Novel selective anti-androgens with a diphenylpentane skeleton. Bioorg Med Chem Lett 20:6661-6 (2010) [PubMed]  Article 
Target
Name:
Vitamin D3 receptor
Synonyms:
1,25-dihydroxyvitamin D3 receptor | NR1I1 | Nuclear receptor subfamily 1 group I member 1 | Retinoic acid receptor RXR-alpha/Vitamin D3 receptor | VDR | VDR_HUMAN
Type:
Protein
Mol. Mass.:
48288.72
Organism:
Homo sapiens (Human)
Description:
P11473
Residue:
427
Sequence:
MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLEVFGNEIS
  
Inhibitor
Name:
BDBM50329720
Synonyms:
(2S)-3-(4-(3-(4-(2-hydroxy-3,3-dimethyl-4-(naphthalen-2-yl)butoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol | CHEMBL1269465
Type:
Small organic molecule
Emp. Form.:
C38H48O5
Mol. Mass.:
584.7847
SMILES:
CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OCC(O)C(C)(C)Cc2ccc3ccccc3c2)c(C)c1 |r|
Structure:
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