Reaction Details Report a problem with these data
Target
Pteridine reductase 1
Ligand
BDBM10443
Substrate
n/a
Meas. Tech.
ChEMBL_702836 (CHEMBL1655366)
IC50
390000±n/a nM
Citation
 Shi, K; Huang, Q; Huang, Y; Lee, TC; Yu, H Reducing the brittleness of zein films through chemical modification. J Agric Food Chem 59:56-61 (2011) [PubMed]  Article 
Target
Name:
Pteridine reductase 1
Synonyms:
HMTXR | PTR1 | PTR1_LEIMA
Type:
PROTEIN
Mol. Mass.:
30459.34
Organism:
Leishmania major
Description:
ChEMBL_1470027
Residue:
288
Sequence:
MTAPTVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRFAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTRA
  
Inhibitor
Name:
BDBM10443
Synonyms:
2-methylquinolin-4-amine | 4-Aminoquinaldine 4
Type:
Small organic molecule
Emp. Form.:
C10H10N2
Mol. Mass.:
158.1998
SMILES:
Cc1cc(N)c2ccccc2n1
Structure:
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