Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 5
Ligand
BDBM50378978
Substrate
n/a
Meas. Tech.
ChEMBL_809511 (CHEMBL2015428)
Kd
17500±n/a nM
Citation
 Navratilova, I; Besnard, J; Hopkins, AL Screening for GPCR Ligands Using Surface Plasmon Resonance. ACS Med Chem Lett 2:549-554 (2011) [PubMed]  Article 
Target
Name:
C-C chemokine receptor type 5
Synonyms:
C-C CKR-5 | C-C chemokine receptor type 5 | CC-CKR-5 | CCR-5 | CCR5 | CCR5/mu opioid receptor complex | CCR5_HUMAN | CD_antigen=CD195 | CHEMR13 | CMKBR5 | HIV-1 fusion coreceptor
Type:
Enzyme
Mol. Mass.:
40540.21
Organism:
Homo sapiens (Human)
Description:
P51681
Residue:
352
Sequence:
MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
  
Inhibitor
Name:
BDBM50378978
Synonyms:
CHEMBL2011440
Type:
Small organic molecule
Emp. Form.:
C9H6Cl3N3O3S2
Mol. Mass.:
374.651
SMILES:
COc1nc(Cl)c(Cl)nc1NS(=O)(=O)c1ccc(Cl)s1
Structure:
Search PDB for entries with ligand similarity: