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Target
Prostate-specific antigen
Ligand
BDBM50379839
Substrate
n/a
Meas. Tech.
ChEMBL_809739 (CHEMBL2016158)
IC50
226±n/a nM
Citation
 Liang, G; Chen, X; Aldous, S; Pu, SF; Mehdi, S; Powers, E; Xia, T; Wang, R Human kallikrein 6 inhibitors with a para-amidobenzylanmine P1 group identified through virtual screening. Bioorg Med Chem Lett 22:2450-5 (2012) [PubMed]  Article 
Target
Name:
Prostate-specific antigen
Synonyms:
APS | Gamma-seminoprotein | KLK3 | KLK3_HUMAN | Kallikrein-3 | P-30 antigen | PSA | Prostate specific antigen | Prostate-specific antigen | Semenogelase | Seminin
Type:
PROTEIN
Mol. Mass.:
28747.53
Organism:
Homo sapiens (Human)
Description:
ChEMBL_959198
Residue:
261
Sequence:
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP
  
Inhibitor
Name:
BDBM50379839
Synonyms:
CHEMBL2011751
Type:
Small organic molecule
Emp. Form.:
C33H27NO8
Mol. Mass.:
565.5694
SMILES:
Oc1ccc(C[C@H]2[C@H](N(C(=O)Oc3cccc(c3)C(=O)OCc3ccccc3)C2=O)C(=O)OCc2ccccc2)cc1 |r|
Structure:
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