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Target
Testis-specific serine/threonine-protein kinase 2
Ligand
BDBM50362169
Substrate
n/a
Meas. Tech.
ChEMBL_813710 (CHEMBL2019912)
IC50
>30000±n/a nM
Citation
 Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE Discovery and Hit-to-Lead Optimization of Non-ATP Competitive MK2 (MAPKAPK2) Inhibitors. ACS Med Chem Lett 2:632-637 (2011) [PubMed]  Article 
Target
Name:
Testis-specific serine/threonine-protein kinase 2
Synonyms:
DGSG | SPOGA2 | STK22B | TSSK2 | TSSK2_HUMAN
Type:
PROTEIN
Mol. Mass.:
40954.93
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1459845
Residue:
358
Sequence:
MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST
  
Inhibitor
Name:
BDBM50362169
Synonyms:
CHEMBL1938680
Type:
Small organic molecule
Emp. Form.:
C21H20ClN3O2
Mol. Mass.:
381.855
SMILES:
Clc1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1
Structure:
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