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Target
Fructose-bisphosphate aldolase, glycosomal
Ligand
BDBM50330437
Substrate
n/a
Meas. Tech.
ChEMBL_813853 (CHEMBL2020222)
IC50
10000±n/a nM
Citation
 Mabiala-Bassiloua, CG; Arthus-Cartier, G; Hannaert, V; Thérisod, H; Sygusch, J; Thérisod, M Mannitol Bis-phosphate Based Inhibitors of Fructose 1,6-Bisphosphate Aldolases. ACS Med Chem Lett 2:804-808 (2011) [PubMed]  Article 
Target
Name:
Fructose-bisphosphate aldolase, glycosomal
Synonyms:
ALD | ALF_TRYBB | Fructose-bisphosphate aldoloase, glycosomal
Type:
PROTEIN
Mol. Mass.:
41192.02
Organism:
Trypanosoma brucei brucei
Description:
ChEMBL_813853
Residue:
372
Sequence:
MSKRVEVLLTQLPAYNRLKTPYEAELIETAKKMTAPGKGLLAADESTGSCSKRFAGIGLSNTAEHRRQYRALMLECEGFEQYISGVILHDETVYQKAKTGETFPQYLRRRGVVPGIKTDCGLEPLVEGAKGEQMTAGLDGYIKRAKKYYAMGCRFCKWRNVYKIQNGTVSEAVVRFNAETLARYAILSQLCGLVPIVEPEVMIDGTHDIETCQRVSQHVWSEVVSALHRHGVVWEGCLLKPNMVVPGAESGLKGHAEQVAEYTVKTLARVIPPALPGVTFLSGGLSEVMASEYLNAMNNCPLPRPWKLTFSYARALQSSAIKRWGGKESGVEAGRRAFMHRAKMNSLAQLGKYNRADDDKDSQSLYVAGNTY
  
Inhibitor
Name:
BDBM50330437
Synonyms:
1,6-di-O-phosphono-D-fructose | 2,3,4-trihydroxy-5-oxohexane-1,6-diyl bis(dihydrogen phosphate) | CHEMBL1235112
Type:
Small organic molecule
Emp. Form.:
C6H14O12P2
Mol. Mass.:
340.1157
SMILES:
OC(COP(O)(O)=O)[C@@H](O)C(=O)[C@H](O)COP(O)(O)=O |r|
Structure:
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