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Target
Myeloblastin
Ligand
BDBM50384104
Substrate
n/a
Meas. Tech.
ChEMBL_819862 (CHEMBL2034576)
IC50
5000±n/a nM
Citation
 Santana, AB; Lucas, SD; Gonçalves, LM; Correia, HF; Cardote, TA; Guedes, RC; Iley, J; Moreira, R N-Acyl and N-sulfonyloxazolidine-2,4-diones are pseudo-irreversible inhibitors of serine proteases. Bioorg Med Chem Lett 22:3993-7 (2012) [PubMed]  Article 
Target
Name:
Myeloblastin
Synonyms:
Leukocyte proteinase 3 | MBN | PRTN3 | PRTN3_HUMAN
Type:
PROTEIN
Mol. Mass.:
27816.30
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1463425
Residue:
256
Sequence:
MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVEAKGRP
  
Inhibitor
Name:
BDBM50384104
Synonyms:
CHEMBL2029559
Type:
Small organic molecule
Emp. Form.:
C17H13NO5
Mol. Mass.:
311.2888
SMILES:
COc1ccc(cc1)C(=O)n1c(O)c(oc1=O)-c1ccccc1
Structure:
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