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Target
Cathepsin G
Ligand
BDBM50384108
Substrate
n/a
Meas. Tech.
ChEMBL_819861 (CHEMBL2034575)
IC50
2100±n/a nM
Citation
 Santana, AB; Lucas, SD; Gonçalves, LM; Correia, HF; Cardote, TA; Guedes, RC; Iley, J; Moreira, R N-Acyl and N-sulfonyloxazolidine-2,4-diones are pseudo-irreversible inhibitors of serine proteases. Bioorg Med Chem Lett 22:3993-7 (2012) [PubMed]  Article 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM50384108
Synonyms:
CHEMBL2029554
Type:
Small organic molecule
Emp. Form.:
C12H13NO3
Mol. Mass.:
219.2365
SMILES:
CC1(C)OC(=O)N(Cc2ccccc2)C1=O
Structure:
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