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Target
Histone deacetylase-like amidohydrolase
Ligand
BDBM50386452
Substrate
n/a
Meas. Tech.
ChEMBL_827139 (CHEMBL2050423)
IC50
32000±n/a nM
Citation
 Baud, MG; Leiser, T; Haus, P; Samlal, S; Wong, AC; Wood, RJ; Petrucci, V; Gunaratnam, M; Hughes, SM; Buluwela, L; Turlais, F; Neidle, S; Meyer-Almes, FJ; White, AJ; Fuchter, MJ Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets. J Med Chem 55:1731-50 (2012) [PubMed]  Article 
Target
Name:
Histone deacetylase-like amidohydrolase
Synonyms:
HDAH_ALCSD | hdaH | hdaH1
Type:
PROTEIN
Mol. Mass.:
39419.78
Organism:
Alcaligenes sp. (strain DSM 11172) (Bordetella sp. (strain FB188))
Description:
ChEMBL_827139
Residue:
369
Sequence:
MAIGYVWNTLYGWVDTGTGSLAAANLTARMQPISHHLAHPDTKRRFHELVCASGQIEHLTPIAAVAATDADILRAHSAAHLENMKRVSNLPTGGDTGDGITMMGNGGLEIARLSAGGAVELTRRVATGELSAGYALVNPPGHHAPHNAAMGFCIFNNTSVAAGYARAVLGMERVAILDWDVHHGNGTQDIWWNDPSVLTISLHQHLCFPPDSGYSTERGAGNGHGYNINVPLPPGSGNAAYLHAMDQVVLHALRAYRPQLIIVGSGFDASMLDPLARMMVTADGFRQMARRTIDCAADICDGRIVFVQEGGYSPHYLPFCGLAVIEELTGVRSLPDPYHEFLAGMGGNTLLDAERAAIEEIVPLLADIR
  
Inhibitor
Name:
BDBM50386452
Synonyms:
CHEMBL2047680
Type:
Small organic molecule
Emp. Form.:
C11H14BrN3O2S
Mol. Mass.:
332.217
SMILES:
NN=C(Cc1ccc(O)c(Br)c1)C(=O)NCCS |w:1.0|
Structure:
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