Reaction Details Report a problem with these data
Target
Orphan methyltransferase M.SssI
Ligand
BDBM50389484
Substrate
n/a
Meas. Tech.
ChEMBL_832310 (CHEMBL2066848)
Ki
6000000±n/a nM
Citation
 Plitta, B; Adamska, E; Giel-Pietraszuk, M; Fedoruk-Wyszomirska, A; Naskret-Barciszewska, M; Markiewicz, WT; Barciszewski, J New cytosine derivatives as inhibitors of DNA methylation. Eur J Med Chem 55:243-54 (2012) [PubMed]  Article 
Target
Name:
Orphan methyltransferase M.SssI
Synonyms:
CpG DNA methylase | M.SssI methyltransferase | MTSI_SPISQ | mssSI | sssIM
Type:
Protein
Mol. Mass.:
44323.75
Organism:
Spiroplasma monobiae strain MQ-1
Description:
P15840
Residue:
386
Sequence:
MSKVENKTKKLRVFEAFAGIGAQRKALEKVRKDEYEIVGLAEWYVPAIVMYQAIHNNFHTKLEYKSVSREEMIDYLENKTLSWNSKNPVSNGYWKRKKDDELKIIYNAIKLSEKEGNIFDIRDLYKRTLKNIDLLTYSFPCQDLSQQGIQKGMKRGSGTRSGLLWEIERALDSTEKNDLPKYLLMENVGALLHKKNEEELNQWKQKLESLGYQNSIEVLNAADFGSSQARRRVFMISTLNEFVELPKGDKKPKSIKKVLNKIVSEKDILNNLLKYNLTEFKKTKSNINKASLIGYSKFNSEGYVYDPEFTGPTLTASGANSRIKIKDGSNIRKMNSDETFLYIGFDSQDGKRVNEIEFLTENQKIFVCGNSISVEVLEAIIDKIGG
  
Inhibitor
Name:
BDBM50389484
Synonyms:
CHEMBL2063065
Type:
Small organic molecule
Emp. Form.:
C6H9N3O
Mol. Mass.:
139.1552
SMILES:
CCNc1cc[nH]c(=O)n1
Structure:
Search PDB for entries with ligand similarity: