Reaction Details Report a problem with these data
Target
Intracellular chorismate mutase
Ligand
BDBM50390440
Substrate
n/a
Meas. Tech.
ChEMBL_834286 (CHEMBL2073106)
IC50
23880±n/a nM
Citation
 Adepu, R; Shiva Kumar, K; Sandra, S; Rambabu, D; Rama Krishna, G; Malla Reddy, C; Kandale, A; Misra, P; Pal, M C-N bond formation under Cu-catalysis: synthesis and in vitro evaluation of N-aryl substituted thieno[2,3-d]pyrimidin-4(3H)-ones against chorismate mutase. Bioorg Med Chem 20:5127-38 (2012) [PubMed]  Article 
Target
Name:
Intracellular chorismate mutase
Synonyms:
CHMU_MYCTU | MT0975
Type:
PROTEIN
Mol. Mass.:
11771.52
Organism:
Mycobacterium tuberculosis
Description:
ChEMBL_834286
Residue:
105
Sequence:
MRPEPPHHENAELAAMNLEMLESQPVPEIDTLREEIDRLDAEILALVKRRAEVSKAIGKARMASGGTRLVHSREMKVIERYSELGPDGKDLAILLLRLGRGRLGH
  
Inhibitor
Name:
BDBM50390440
Synonyms:
CHEMBL2071373
Type:
Small organic molecule
Emp. Form.:
C21H21N3O4S
Mol. Mass.:
411.474
SMILES:
CC(C)(C)OC(=O)N1CCc2c(C1)sc1ncn(-c3cccc(C=O)c3)c(=O)c21
Structure:
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