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Target
Histone H4
Ligand
BDBM50397030
Substrate
n/a
Meas. Tech.
ChEMBL_863123 (CHEMBL2175621)
Kd
23800±n/a nM
Citation
 Wang, J; Chen, L; Sinha, SH; Liang, Z; Chai, H; Muniyan, S; Chou, YW; Yang, C; Yan, L; Feng, Y; Li, KK; Lin, MF; Jiang, H; Zheng, YG; Luo, C Pharmacophore-based virtual screening and biological evaluation of small molecule inhibitors for protein arginine methylation. J Med Chem 55:7978-87 (2012) [PubMed]  Article 
Target
Name:
Histone H4
Synonyms:
andH4/M | and | andH4/N | andH4/O | andH4/B | andH4/C | andH4/H | andH4/I | andH4/J | andH4/K | andH4/D | andH4/E | andH4/G | H4_HUMAN | H4C1 | H4/A | H4FA | HIST1H4A | H4/I | H4FI | HIST1H4B | H4/G | H4FG | HIST1H4C | H4/B | H4FB | HIST1H4D | H4/J | H4FJ | HIST1H4E | H4/C | H4FC | HIST1H4F | H4/H | H4FH | HIST1H4H | H4/M | H4FM | HIST1H4I | H4/E | H4FE | HIST1H4J | H4/D | H4FD | HIST1H4K | H4/K | H4FK | HIST1H4L | H4/N | H4F2 | H4FN | HIST2H4 | HIST2H4A | H4/O | H4FO | HIST2H4B | H4-16 | HIST4H4
Type:
Protein
Mol. Mass.:
11386.36
Organism:
Human
Description:
P62805
Residue:
103
Sequence:
MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
  
Inhibitor
Name:
BDBM50397030
Synonyms:
CHEMBL2171189
Type:
Small organic molecule
Emp. Form.:
C35H24N2O5
Mol. Mass.:
n/a
SMILES:
Oc1ccc(cc1NC(=O)c1cccc2ccccc12)C(=O)c1ccc(O)c(NC(=O)c2cccc3ccccc23)c1
Structure:
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