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Target
Bcl-2-related protein A1
Ligand
BDBM50397583
Substrate
n/a
Meas. Tech.
ChEMBL_862260 (CHEMBL2173037)
EC50
21500±n/a nM
Citation
 Saugues, E; Debaud, AL; Anizon, F; Bonnefoy, N; Moreau, P Synthesis and biological activities of polyquinoline derivatives: new Bcl-2 family protein modulators. Eur J Med Chem 57:112-25 (2012) [PubMed]  Article 
Target
Name:
Bcl-2-related protein A1
Synonyms:
B2LA1_HUMAN | BCL2A1 | BCL2L5 | BFL1 | Bcl-2-like protein 5 | GRS | HBPA1 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS
Type:
Apoptosis regulator protein
Mol. Mass.:
20130.01
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
175
Sequence:
MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
  
Inhibitor
Name:
BDBM50397583
Synonyms:
CHEMBL2171509
Type:
Small organic molecule
Emp. Form.:
C29H32N4
Mol. Mass.:
436.5912
SMILES:
CC(C)c1cc(cc2nc(ccc12)N1CCCC1)-c1cc2ccccc2nc1N1CCCC1
Structure:
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