Reaction Details Report a problem with these data
Target
P2X purinoceptor 1
Ligand
BDBM50399190
Substrate
n/a
Meas. Tech.
ChEMBL_876874 (CHEMBL2184468)
IC50
602±n/a nM
Citation
 Hernandez-Olmos, V; Abdelrahman, A; El-Tayeb, A; Freudendahl, D; Weinhausen, S; Müller, CE N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists. J Med Chem 55:9576-88 (2012) [PubMed]  Article 
Target
Name:
P2X purinoceptor 1
Synonyms:
ATP receptor | P2RX1 | P2RX1_HUMAN | P2X1 | Purinergic receptor | Purinergic, P2X
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44992.65
Organism:
Homo sapiens (Human)
Description:
Purinergic, P2X 0 HUMAN::P51575
Residue:
399
Sequence:
MARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTSSGLISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEHPEGGICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVKTCEIFGWCPVEVDDDIPRPALLREAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESGQNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEKNLSPGFNFRFARHFVENGTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKRHYYKQKKFKYAEDMGPGAAERDLAATSSTLGLQENMRTS
  
Inhibitor
Name:
BDBM50399190
Synonyms:
CHEMBL2180149
Type:
Small organic molecule
Emp. Form.:
C26H21NO
Mol. Mass.:
363.451
SMILES:
OC1(c2ccccc2)c2ccccc2N(Cc2ccccc2)c2ccccc12
Structure:
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