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Target
Apoptosis regulator Bcl-2
Ligand
BDBM50400178
Substrate
n/a
Meas. Tech.
ChEMBL_878600 (CHEMBL2188685)
Ki
44±n/a nM
Citation
 Zhang, Z; Li, X; Song, T; Zhao, Y; Feng, Y An anthraquinone scaffold for putative, two-face Bim BH3a-helix mimic. J Med Chem 55:10735-41 (2012) [PubMed]  Article 
Target
Name:
Apoptosis regulator Bcl-2
Synonyms:
Apoptosis regulator Bcl-2 Protein | B-cell lymphoma 2 protein (Bcl-2) | BCL-2 | BCL2 | BCL2_HUMAN | Bcl-2 Protein
Type:
Homodimer or heterodimer
Mol. Mass.:
26269.11
Organism:
Homo sapiens (Human)
Description:
P10415
Residue:
239
Sequence:
MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
  
Inhibitor
Name:
BDBM50400178
Synonyms:
2,3‐dihydroxy‐6‐[(4‐ methylphenyl)sulfanyl]anthracene‐9,10‐dione (Ligand 5) | CHEMBL2180318
Type:
Small organic molecule
Emp. Form.:
C21H14O4S
Mol. Mass.:
362.398
SMILES:
Cc1ccc(Sc2ccc3C(=O)c4cc(O)c(O)cc4C(=O)c3c2)cc1
Structure:
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