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Target
Arylsulfatase
Ligand
BDBM50400984
Substrate
n/a
Meas. Tech.
ChEMBL_879573 (CHEMBL2209023)
IC50
10000000±n/a nM
Citation
 Lenger, J; Schröder, M; Ennemann, EC; Müller, B; Wong, CH; Noll, T; Dierks, T; Hanson, SR; Sewald, N Evaluation of sulfatase-directed quinone methide traps for proteomics. Bioorg Med Chem 20:622-7 (2012) [PubMed]  Article 
Target
Name:
Arylsulfatase
Synonyms:
AS | ATSA_KLEPN | Aryl-sulfate sulphohydrolase | atsA
Type:
PROTEIN
Mol. Mass.:
64155.34
Organism:
Klebsiella pneumoniae
Description:
ChEMBL_879573
Residue:
577
Sequence:
MNKKAMAAAVSMILAGGAHAAQQERPNVIVIIADDMGYSDISPFGGEIPTPNLQAMAEQGMRMSQYYTSPMSAPARSMLLTGNSNQQAGMGGMWWYDSTIGKEGYELRLTDRVTTMAERFKDAGYNTLMAGKWHLGFVPGATPKERGFNHAFAFMGGGTSHFNDAIPLGTVEAFHTYYTRDGERVSLPDDFYSSEAYARQMNSWIKATPKEQPVFAWLAFTAPHDPLQAPDEWIKRFKGQYEQGYAEVYRQRIARLKALGIIHDDTPLPHLELDKEWEALTPEQQKYTAKVMQVYAAMIANMDAQIGTLMETLKQTGRDKNTLLVFLTDNGANPAQGFYYESTPEFWKQFDNSYDNVGRKGSFVSYGPHWANVSNAPYANYHKTTSAQGGINTDFMISGPGITRHGKIDASTMAVYDVAPTLYEFAGIDPNKSLAKKPVLPMIGVSFKRYLTGEVQEPPRGNYGVELHHQAAWVDGEWKLRRLVPRGLTAGDAPWQLFNLHDDPLETHDVAAEHPDRVKAMSEAYEAFAKRTMVTKAQGKMIDYVGIDSKTGRYLAVDPATMKPVPAPQAIPVSEIH
  
Inhibitor
Name:
BDBM50400984
Synonyms:
CHEMBL2205725
Type:
Small organic molecule
Emp. Form.:
C7H6F2O4S
Mol. Mass.:
224.182
SMILES:
OS(=O)(=O)Oc1ccccc1C(F)F
Structure:
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