Reaction Details Report a problem with these data
Target
Chorismate synthase
Ligand
BDBM50421345
Substrate
n/a
Meas. Tech.
ChEBML_49433
Kd
>20000±n/a nM
Citation
 Ramjee, MK; Coggins, JR; Hawkes, TR; Lowe, DJ; Thorneley, RN The stoichiometry of binding of flavin mononucleotide (FMN) hydroquinone to Escherichia coli chorismate synthase Bioorg Med Chem Lett 3:1409-1414 (1993)    Article 
Target
Name:
Chorismate synthase
Synonyms:
AROC_STRPN | aroC
Type:
PROTEIN
Mol. Mass.:
42869.22
Organism:
Streptococcus pneumoniae
Description:
ChEMBL_49433
Residue:
388
Sequence:
MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYGRGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRKITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANHVVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVVETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEILWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKATVERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY
  
Inhibitor
Name:
BDBM50421345
Synonyms:
E101a | RIBOFLAVIN 5'-PHOSPHATE | Riboflavin 5''-Phosphate
Type:
Small organic molecule
Emp. Form.:
C17H21N4O9P
Mol. Mass.:
456.3438
SMILES:
Cc1cc2nc3c(nc(=O)[nH]c3=O)n(C[C@H](O)[C@H](O)[C@H](O)COP(O)(O)=O)c2cc1C
Structure:
Search PDB for entries with ligand similarity: