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Target
Spermidine synthase
Ligand
BDBM50095450
Substrate
n/a
Meas. Tech.
ChEMBL_201156 (CHEMBL802181)
IC50
400±n/a nM
Citation
 Tang, KC; Mariuza, R; Coward, JK Synthesis and evaluation of some stable multisubstrate adducts as specific inhibitors of spermidine synthase. J Med Chem 24:1277-84 (1982) [PubMed]  Article 
Target
Name:
Spermidine synthase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
33991.53
Organism:
Rattus norvegicus
Description:
ChEMBL_201181
Residue:
302
Sequence:
MEPGPDGPAAPGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIEVSKKFLPGMAVGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGILCCQGECQWLHLDLIKEMRHFCKSLFPVVSYAYCTIPTYPSGQIGFMLCSKNPSTNFREPVQQLTQAQVEQMQLKYYNSDMHRAAFVLPEFTRKALNDIS
  
Inhibitor
Name:
BDBM50095450
Synonyms:
2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-5-(6-amino-purin-9-yl)-tetrahydro-furan-3,4-diol | CHEMBL330673
Type:
Small organic molecule
Emp. Form.:
C18H31N7O3S
Mol. Mass.:
425.549
SMILES:
NCCCCCC(CCN)SC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Structure:
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