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Target
Beta-2 adrenergic receptor
Ligand
BDBM50405521
Substrate
n/a
Meas. Tech.
ChEMBL_38001 (CHEMBL651635)
Kd
105±n/a nM
Citation
 Baldwin, JJ; Denny, GH; Hirschmann, R; Freedman, MB; Ponticello, GS; Gross, DM; Sweet, CS Beta 1-selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazole class. J Med Chem 26:950-7 (1983) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2_CAVPO | Adrb2 | adrenergic Beta2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46993.24
Organism:
GUINEA PIG
Description:
adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4
Residue:
418
Sequence:
MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
  
Inhibitor
Name:
BDBM50405521
Synonyms:
ALO 1401-02 | ALO-1401-02 | BETAXOLOL HYDROCHLORIDE | Betaxolol
Type:
Small organic molecule
Emp. Form.:
C18H29NO3
Mol. Mass.:
307.4278
SMILES:
CC(C)NCC(O)COc1ccc(CCOCC2CC2)cc1
Structure:
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