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Target
Dopamine beta-hydroxylase
Ligand
BDBM50406072
Substrate
n/a
Meas. Tech.
ChEMBL_59302 (CHEMBL669437)
IC50
147910.84±n/a nM
Citation
 Hahn, M; Rogers, D Receptor surface models. 2. Application to quantitative structure-activity relationships studies. J Med Chem 38:2091-102 (1995) [PubMed]  Article 
Target
Name:
Dopamine beta-hydroxylase
Synonyms:
DBH | DOPO_HUMAN | Dopamine beta-monooxygenase | Soluble dopamine beta-hydroxylase
Type:
PROTEIN
Mol. Mass.:
69062.68
Organism:
Homo sapiens (Human)
Description:
ChEMBL_59428
Residue:
617
Sequence:
MPALSRWASLPGPSMREAAFMYSTAVAIFLVILVAALQGSAPRESPLPYHIPLDPEGSLELSWNVSYTQEAIHFQLLVRRLKAGVLFGMSDRGELENADLVVLWTDGDTAYFADAWSDQKGQIHLDPQQDYQLLQVQRTPEGLTLLFKRPFGTCDPKDYLIEDGTVHLVYGILEEPFRSLEAINGSGLQMGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQETTYWCYIKELPKGFSRHHIIKYEPIVTKGNEALVHHMEVFQCAPEMDSVPHFSGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGIHIFASQLHTHLTGRKVVTVLVRDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTEDRELATVGGFGILEEMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFNNEDVCTCPQASVSQQFTSVPWNSFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLPKVISTLEEPTPQCPTSQGRSPAGPTVVSIGGGKG
  
Inhibitor
Name:
BDBM50406072
Synonyms:
CHEMBL65265
Type:
Small organic molecule
Emp. Form.:
C11H12N2S
Mol. Mass.:
204.291
SMILES:
Cc1ccc(Cn2cc[nH]c2=S)cc1
Structure:
Search PDB for entries with ligand similarity: