Reaction Details Report a problem with these data
Target
Neuronal acetylcholine receptor subunit alpha-9
Ligand
BDBM50408542
Substrate
n/a
Meas. Tech.
ChEMBL_142899 (CHEMBL748708)
Kd
0.036±n/a nM
Citation
 Horti, AG; Scheffel, U; Kimes, AS; Musachio, JL; Ravert, HT; Mathews, WB; Zhan, Y; Finley, PA; London, ED; Dannals, RF Synthesis and evaluation of N-[11C]methylated analogues of epibatidine as tracers for positron emission tomographic studies of nicotinic acetylcholine receptors. J Med Chem 41:4199-206 (1998) [PubMed]  Article 
Target
Name:
Neuronal acetylcholine receptor subunit alpha-9
Synonyms:
ACHA9_RAT | Acra9 | Cholinergic, Nicotinic Muscle | Chrna9 | NACHR alpha 9 | Neuronal acetylcholine receptor subunit alpha-9 | Nicotinic acetylcholine receptor subunit alpha 9
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54522.69
Organism:
RAT
Description:
Cholinergic, Nicotinic Muscle 0 RAT::P43144
Residue:
479
Sequence:
MNRPHSCLSFCWMYFAASGIRAVETANGKYAQKLFSDLFEDYSSALRPVEDTDAVLNVTLQVTLSQIKDMDERNQILTAYLWIRQTWHDAYLTWDRDQYDRLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDGLITWDSPAITKSSCVVDVTYFPFDSQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDVEWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYLPAASGEKVSLGVTILLAMTVFQLMVAEIMPASENVPLIGKYYIATMALITASTALTIMVMNIHFCGAEARPVPHWAKVVILKYMSRILFVYDVGESCLSPRHSQEPEQVTKVYSKLPESNLKTSRNKDLSRKKEVRKLLKNDLGYQGGIPQNTDSYCARYEALTKNIEYIAKCLKDHKATNSKGSEWKKVAKVIDRFFMWIFFAMVFVMTVLIIARAD
  
Inhibitor
Name:
BDBM50408542
Synonyms:
CHEMBL337276
Type:
Small organic molecule
Emp. Form.:
C13H16BrN
Mol. Mass.:
266.177
SMILES:
CN1C2CCC1C(C2)c1ccc(Br)cc1 |TLB:8:6:1:4.3|
Structure:
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