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Target
B1 bradykinin receptor
Ligand
BDBM50408806
Substrate
n/a
Meas. Tech.
ChEMBL_40139 (CHEMBL656133)
Kd
7.94±n/a nM
Citation
 Galoppini, C; Meini, S; Tancredi, M; Di Fenza, A; Triolo, A; Quartara, L; Maggi, CA; Formaggio, F; Toniolo, C; Mazzucco, S; Papini, A; Rovero, P A new class of pseudopeptide antagonists of the kinin B1 receptor containing alkyl spacers. J Med Chem 42:409-14 (1999) [PubMed]  Article 
Target
Name:
B1 bradykinin receptor
Synonyms:
B1 BRADYKININ | B1R | B1bkr | BK-1 receptor | BKRB1_RAT | Bdkrb1 | Bkr | Bradykinin B1 receptor | KB1 | Kinin B1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38389.97
Organism:
RAT
Description:
B1 BRADYKININ BDKRB1 RAT::P97583
Residue:
337
Sequence:
MASEVLLELQPSNRSLQAPANITSCESALEDWDLLYRVLPGFVITICFFGLLGNLLVLSFFLLPWRQWWWQQRQRQQRLTIAEIYLANLAASDLVFVLGLPFWAENIGNRFNWPFGTDLCRVVSGVIKANLFVSIFLVVAISQDRYRLLVYPMTSWGYRRRRQAQATCLLIWVAGGLLSIPTFLLRSVKVVPDLNVSACILLFPHEAWHFARMVELNVLGFLLPVTAIIFFNYHILASLRGQKEASRTRCGGPKGSKTTGLILTLVASFLVCWCPYHFFAFLDFLVQVRVIQDCSWKEITDLGLQLANFFAFVNSCLNPLIYVFAGRLLKTRVLGTL
  
Inhibitor
Name:
BDBM50408806
Synonyms:
B-9858 | CHEMBL410358
Type:
Small organic molecule
Emp. Form.:
C64H95N15O13
Mol. Mass.:
1282.5318
SMILES:
NCCCC[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CC(O)C[C@H]1C(=O)NCC(=O)N[C@@H](C1Cc2ccccc2C1)C(=O)N[C@@H](CO)C(=O)N[C@H](C1Cc2ccccc2C1)C(=O)N1C(C[C@@H]2CCCC[C@H]12)C(O)=O
Structure:
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