Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50415180
Substrate
n/a
Meas. Tech.
ChEMBL_601032 (CHEMBL1069169)
Ki
100±n/a nM
Citation
 Balo, MC; Brea, J; Caamaño, O; Fernández, F; García-Mera, X; López, C; Loza, MI; Nieto, MI; Rodríguez-Borges, JE Synthesis and pharmacological evaluation of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists. Bioorg Med Chem 17:6755-60 (2009) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50415180
Synonyms:
CHEMBL594963
Type:
Small organic molecule
Emp. Form.:
C20H20N4O3S
Mol. Mass.:
396.463
SMILES:
Cn1c(Cc2cccs2)nc2n(Cc3ccco3)c(=O)n(CC3CC3)c(=O)c12
Structure:
Search PDB for entries with ligand similarity: