Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50415448
Substrate
n/a
Meas. Tech.
ChEMBL_611640 (CHEMBL1071010)
Ki
588.84±n/a nM
Citation
 Rodríguez-Borges, JE; García-Mera, X; Balo, MC; Brea, J; Caamaño, O; Fernández, F; López, C; Loza, MI; Nieto, MI Synthesis and pharmacological evaluation of novel 1,3,8- and 1,3,7,8-substituted xanthines as adenosine receptor antagonists. Bioorg Med Chem 18:2001-9 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50415448
Synonyms:
CHEMBL599817
Type:
Small organic molecule
Emp. Form.:
C18H22N4O3S
Mol. Mass.:
374.457
SMILES:
CCCn1c(=O)n(CCS(=O)CC)c2nc([nH]c2c1=O)-c1ccccc1
Structure:
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