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Target
Kappa-type opioid receptor
Ligand
BDBM50417600
Substrate
n/a
Meas. Tech.
ChEMBL_699954 (CHEMBL1646361)
Ki
200±n/a nM
Citation
 Zhang, C; Westaway, SM; Speake, JD; Bishop, MJ; Goetz, AS; Carballo, LH; Hu, M; Epperly, AH Tetrahydroquinoline derivatives as opioid receptor antagonists. Bioorg Med Chem Lett 21:670-6 (2011) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM50417600
Synonyms:
CHEMBL1642759
Type:
Small organic molecule
Emp. Form.:
C26H33N3O
Mol. Mass.:
403.5597
SMILES:
Cc1cc(CNCCC2=CCCCC2)ccc1N1CCCc2cc(ccc12)C(N)=O |t:8|
Structure:
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