Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50343141
Substrate
n/a
Meas. Tech.
ChEMBL_770381 (CHEMBL1833690)
EC50
18.62±n/a nM
Citation
 Christiansen, E; Urban, C; Grundmann, M; Due-Hansen, ME; Hagesaether, E; Schmidt, J; Pardo, L; Ullrich, S; Kostenis, E; Kassack, M; Ulven, T Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties. J Med Chem 54:6691-703 (2011) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50343141
Synonyms:
3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)propanoic acid | CHEMBL1773261
Type:
Small organic molecule
Emp. Form.:
C23H23NO2
Mol. Mass.:
345.4342
SMILES:
Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1
Structure:
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