Reaction Details Report a problem with these data
Target
Histamine H3 receptor
Ligand
BDBM50419594
Substrate
n/a
Meas. Tech.
ChEMBL_795215 (CHEMBL1936874)
Ki
60255.96±n/a nM
Citation
 Bordi, F; Rivara, S; Dallaturca, E; Carmi, C; Pala, D; Lodola, A; Vacondio, F; Flammini, L; Bertoni, S; Ballabeni, V; Barocelli, E; Mor, M Dibasic biphenyl H3 receptor antagonists: Steric tolerance for a lipophilic side chain. Eur J Med Chem 48:214-30 (2012) [PubMed]  Article 
Target
Name:
Histamine H3 receptor
Synonyms:
HH3R | HRH3_RAT | Hrh3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
48607.98
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
445
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK
  
Inhibitor
Name:
BDBM50419594
Synonyms:
CHEMBL1934066
Type:
Small organic molecule
Emp. Form.:
C23H31N
Mol. Mass.:
321.4989
SMILES:
CCCCCc1ccc(cc1)-c1ccc(CN2CCCCC2)cc1
Structure:
Search PDB for entries with ligand similarity: