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Target
Solute carrier family 22 member 6
Ligand
BDBM50420204
Substrate
n/a
Meas. Tech.
ChEMBL_836971 (CHEMBL2075811)
IC50
177000±n/a nM
Citation
 Groves, CE; Muñoz, L; Bahn, A; Burckhardt, G; Wright, SH Interaction of cysteine conjugates with human and rabbit organic anion transporter 1. J Pharmacol Exp Ther 304:560-6 (2003) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 6
Synonyms:
OAT1 | Organic anion transporter 1 | PAH transporter | PAHT | Renal organic anion transporter 1 | S22A6_HUMAN | SLC22A6 | hOAT1 | hPAHT | hROAT1
Type:
PROTEIN
Mol. Mass.:
61831.78
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1487359
Residue:
563
Sequence:
MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRWAPTQKEAGIYPRKGKQTRQQQEHQKYMVPLQASAQEKNGL
  
Inhibitor
Name:
BDBM50420204
Synonyms:
CHEMBL2074985
Type:
Small organic molecule
Emp. Form.:
C5H7ClF3NO2S
Mol. Mass.:
237.628
SMILES:
N[C@H](CSC(F)(F)C(F)Cl)C(O)=O |r|
Structure:
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