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Target
Solute carrier family 22 member 2
Ligand
BDBM50403559
Substrate
n/a
Meas. Tech.
ChEMBL_835924 (CHEMBL2077062)
IC50
8000±n/a nM
Citation
 Kakehi, M; Koyabu, N; Nakamura, T; Uchiumi, T; Kuwano, M; Ohtani, H; Sawada, Y Functional characterization of mouse cation transporter mOCT2 compared with mOCT1. Biochem Biophys Res Commun 296:644-50 (2002) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 2
Synonyms:
Oct2 | Organic cation transporter 2 | S22A2_MOUSE | Slc22a2
Type:
PROTEIN
Mol. Mass.:
61838.23
Organism:
Mus musculus
Description:
ChEMBL_835924
Residue:
553
Sequence:
MPTVDDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPNHHCRSPGVAELSQRCGWSPAEELNYTVPGLGSAGEVSFLSQCMRYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWVYDTPGSSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLLVTILINAISGVLMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRTVGICYQIAFTVGLLILAGVAYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNGKSVPVSLQSLTADEDTGMKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRIGRRYPWAVSNMVAGAACLASVFIPDDLQWLKITVACLGRMGITIAYEMVCLVNAELYPTYIRNLAVLVCSSMCDIGGIVTPFLVYRLTDIWLEFPLVVFAVVGLVAGGLVLLLPETKGKALPETIEDAEKMQRPRKKKEKRIYLQVKKAELS
  
Inhibitor
Name:
BDBM50403559
Synonyms:
Brumetadina | CIMETIDINE
Type:
Small organic molecule
Emp. Form.:
C10H16N6S
Mol. Mass.:
252.339
SMILES:
CNC(NCCSCc1[nH]cnc1C)=NC#N |w:14.15|
Structure:
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