Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 6
Ligand
BDBM26197
Substrate
n/a
Meas. Tech.
ChEMBL_838479 (CHEMBL2076050)
Ki
2099000±n/a nM
Citation
 Apiwattanakul, N; Sekine, T; Chairoungdua, A; Kanai, Y; Nakajima, N; Sophasan, S; Endou, H Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Mol Pharmacol 55:847-54 (1999) [PubMed] 
Target
Name:
Solute carrier family 22 member 6
Synonyms:
Oat1 | Organic anion transporter 1 | S22A6_RAT | Slc22a6 | rOAT1 | rROAT1 | renal organic anion transporter 1
Type:
PROTEIN
Mol. Mass.:
60784.17
Organism:
Rattus norvegicus
Description:
ChEMBL_838479
Residue:
551
Sequence:
MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPPHHCRPPANANLSKDGGLEAWLPLDKQGQPESCLRFTSPQWGPPFYNGTEANGTRVTEPCIDGWVYDNSTFPSTIVTEWNLVCSHRAFRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCVFRLLSGMSLASIAINCMTLNVEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLVVSVPFFIAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEEGAKLSIEVLRTSLQKELTLSKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQMASLLLAGICILVNGIIPKSHTIIRTSLAVLGKGCLASSFNCIFLYTGELYPTVIRQTGLGMGSTMARVGSIVSPLVSMTAEFYPSMPLFIFGAVPVVASAVTALLPETLGQPLPDTVQDLKSRSRGKQNQQQQEQQKQMMPLQASTQEKNGL
  
Inhibitor
Name:
BDBM26197
Synonyms:
CHEMBL112 | N-(4-hydroxyphenyl)acetamide | Norco | Paracetamol | US9333197, Acetaminophen | acetaminophen | phenol derivative, 11
Type:
Small organic molecule
Emp. Form.:
C8H9NO2
Mol. Mass.:
151.1626
SMILES:
CC(=O)Nc1ccc(O)cc1
Structure:
Search PDB for entries with ligand similarity: