Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1D
Ligand
BDBM50422020
Substrate
n/a
Meas. Tech.
ChEMBL_1964 (CHEMBL617569)
IC50
63±n/a nM
Citation
 Castro, JL; Baker, R; Guiblin, AR; Hobbs, SC; Jenkins, MR; Russell, MG; Beer, MS; Stanton, JA; Scholey, K; Hargreaves, RJ Synthesis and biological activity of 3-[2-(dimethylamino)ethyl]-5-[(1,1-dioxo-5-methyl-1,2,5-thiadiazolidin- 2-yl)-methyl]-1H-indole and analogues: agonists for the 5-HT1D receptor. J Med Chem 37:3023-32 (1994) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1D
Synonyms:
5HT1D_PIG | HTR1D | Serotonin 1d (5-HT1d) receptor
Type:
PROTEIN
Mol. Mass.:
32680.56
Organism:
Sus scrofa
Description:
ChEMBL_1963
Residue:
291
Sequence:
AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV
  
Inhibitor
Name:
BDBM50422020
Synonyms:
CHEMBL103205
Type:
Small organic molecule
Emp. Form.:
C16H24N4O2S
Mol. Mass.:
336.452
SMILES:
CN(C)CCc1c[nH]c2ccc(CN3CCN(C)S3(=O)=O)cc12
Structure:
Search PDB for entries with ligand similarity: