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Target
Delta-type opioid receptor
Ligand
BDBM50422800
Substrate
n/a
Meas. Tech.
ChEMBL_334062 (CHEMBL861271)
IC50
15.8±n/a nM
Citation
 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Highly potent and selective zwitterionic agonists of the delta-opioid receptor. Part 1. Bioorg Med Chem Lett 16:905-10 (2006) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50422800
Synonyms:
CHEMBL203406
Type:
Small organic molecule
Emp. Form.:
C33H39N3O4
Mol. Mass.:
541.6805
SMILES:
COc1cccc(c1)[C@H](N1C[C@@H](C)N(Cc2ccccc2)C[C@@H]1C)c1ccc2CCN(Cc2c1)C(=O)CC(O)=O
Structure:
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