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Target
Myc proto-oncogene protein
Ligand
BDBM93880
Substrate
n/a
Meas. Tech.
ChEMBL_935266 (CHEMBL2318156)
IC50
33000±n/a nM
Citation
 Yap, JL; Wang, H; Hu, A; Chauhan, J; Jung, KY; Gharavi, RB; Prochownik, EV; Fletcher, S Pharmacophore identification of c-Myc inhibitor 10074-G5. Bioorg Med Chem Lett 23:370-4 (2012) [PubMed]  Article 
Target
Name:
Myc proto-oncogene protein
Synonyms:
BHLHE39 | Class E basic helix-loop-helix protein 39 | MYC | MYC_HUMAN | Proto-oncogene c-Myc | Transcription factor p64
Type:
PROTEIN
Mol. Mass.:
48794.95
Organism:
Homo sapiens (Human)
Description:
ChEMBL_935266
Residue:
439
Sequence:
MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA
  
Inhibitor
Name:
BDBM93880
Synonyms:
4-(7-Nitro-benzo[1,2,5]oxadiazol-4-ylamino)-benzoic acid | 4-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]benzoic acid | 4-[(7-nitrobenzofurazan-4-yl)amino]benzoic acid | MLS001206687 | SMR000516455 | cid_2836606
Type:
Small organic molecule
Emp. Form.:
C13H8N4O5
Mol. Mass.:
300.2264
SMILES:
OC(=O)c1ccc(Nc2ccc([N+]([O-])=O)c3nonc23)cc1
Structure:
Search PDB for entries with ligand similarity: