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Target
Carbonic anhydrase 2
Ligand
BDBM50429928
Substrate
n/a
Meas. Tech.
ChEMBL_945282 (CHEMBL2340480)
Ki
8860±n/a nM
Citation
 Akincioglu, A; Akbaba, Y; Göçer, H; Göksu, S; Gülçin, I; Supuran, CT Novel sulfamides as potential carbonic anhydrase isoenzymes inhibitors. Bioorg Med Chem 21:1379-85 (2013) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50429928
Synonyms:
CHEMBL2333817
Type:
Small organic molecule
Emp. Form.:
C11H16N2O4S
Mol. Mass.:
272.321
SMILES:
COc1cc2CCC(NS(N)(=O)=O)c2cc1OC
Structure:
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