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Target
Carbonic anhydrase 1
Ligand
BDBM50429929
Substrate
n/a
Meas. Tech.
ChEMBL_945283 (CHEMBL2340481)
Ki
1540±n/a nM
Citation
 Akincioglu, A; Akbaba, Y; Göçer, H; Göksu, S; Gülçin, I; Supuran, CT Novel sulfamides as potential carbonic anhydrase isoenzymes inhibitors. Bioorg Med Chem 21:1379-85 (2013) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 1
Synonyms:
CA-I | CA1 | CAB | CAH1_HUMAN | Carbonate dehydratase I | Carbonic anhydrase | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA
Type:
Enzyme
Mol. Mass.:
28873.37
Organism:
Homo sapiens (Human)
Description:
P00915
Residue:
261
Sequence:
MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRASF
  
Inhibitor
Name:
BDBM50429929
Synonyms:
CHEMBL2333822
Type:
Small organic molecule
Emp. Form.:
C9H12N2O2S
Mol. Mass.:
212.269
SMILES:
NS(=O)(=O)NC1Cc2ccccc2C1
Structure:
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