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Target
D(2) dopamine receptor
Ligand
BDBM50184800
Substrate
n/a
Meas. Tech.
ChEMBL_946374 (CHEMBL2346428)
Ki
140±n/a nM
Citation
 Sanna, F; Ortner, B; Hübner, H; Löber, S; Tschammer, N; Gmeiner, P Discovery of dopamine D4 receptor antagonists with planar chirality. Bioorg Med Chem 21:1680-4 (2013) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50184800
Synonyms:
1-Phenyl-4-[(1-phenyl-1H-pyrazol-4-yl)methyl]piperazine | 1-phenyl-4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazine | CHEMBL210405
Type:
Small organic molecule
Emp. Form.:
C20H22N4
Mol. Mass.:
318.4155
SMILES:
C(N1CCN(CC1)c1ccccc1)c1cnn(c1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: