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Target
Myc proto-oncogene protein
Ligand
BDBM50431277
Substrate
n/a
Meas. Tech.
ChEMBL_950755 (CHEMBL2353444)
IC50
60000±n/a nM
Citation
 Zaki, MA; Balachandran, P; Khan, S; Wang, M; Mohammed, R; Hetta, MH; Pasco, DS; Muhammad, I Cytotoxicity and modulation of cancer-related signaling by (Z)- and (E)-3,4,3',5'-tetramethoxystilbene isolated from Eugenia rigida. J Nat Prod 76:679-84 (2013) [PubMed]  Article 
Target
Name:
Myc proto-oncogene protein
Synonyms:
BHLHE39 | Class E basic helix-loop-helix protein 39 | MYC | MYC_HUMAN | Proto-oncogene c-Myc | Transcription factor p64
Type:
PROTEIN
Mol. Mass.:
48794.95
Organism:
Homo sapiens (Human)
Description:
ChEMBL_935266
Residue:
439
Sequence:
MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA
  
Inhibitor
Name:
BDBM50431277
Synonyms:
(Z)-3,4,3'',5''-Tetramethoxystilbene | (Z)-3,4,3',5'-TETRAMETHOXYSTILBENE | (Z)-3,5,30,40-Tetramethoxystilbene
Type:
Small organic molecule
Emp. Form.:
C18H20O4
Mol. Mass.:
300.349
SMILES:
COc1cc(OC)cc(\C=C/c2ccc(OC)c(OC)c2)c1
Structure:
Search PDB for entries with ligand similarity: