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Target
Adenosine receptor A1
Ligand
BDBM50432452
Substrate
n/a
Meas. Tech.
ChEMBL_953457 (CHEMBL2351068)
Ki
132±n/a nM
Citation
 Karlström, S; Nordvall, G; Sohn, D; Hettman, A; Turek, D; Åhlin, K; Kers, A; Claesson, M; Slivo, C; Lo-Alfredsson, Y; Petersson, C; Bessidskaia, G; Svensson, PH; Rein, T; Jerning, E; Malmberg, Å; Ahlgen, C; Ray, C; Vares, L; Ivanov, V; Johansson, R Substituted 7-amino-5-thio-thiazolo[4,5-d]pyrimidines as potent and selective antagonists of the fractalkine receptor (CX3CR1). J Med Chem 56:3177-90 (2013) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50432452
Synonyms:
CHEMBL2349310
Type:
Small organic molecule
Emp. Form.:
C19H25N5OS2
Mol. Mass.:
403.565
SMILES:
CC(C)C[C@H](CO)Nc1nc(S[C@@H](C)c2ccccc2)nc2nc(N)sc12 |r|
Structure:
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