Reaction Details Report a problem with these data
Target
P2X purinoceptor 1
Ligand
BDBM50433071
Substrate
n/a
Meas. Tech.
ChEMBL_955889 (CHEMBL2379815)
IC50
130±n/a nM
Citation
 Jung, KY; Cho, JH; Lee, JS; Kim, HJ; Kim, YC Synthesis and structure-activity relationships of carboxylic acid derivatives of pyridoxal as P2X receptor antagonists. Bioorg Med Chem 21:2643-50 (2013) [PubMed]  Article 
Target
Name:
P2X purinoceptor 1
Synonyms:
P2RX1_MOUSE | P2rx1
Type:
PROTEIN
Mol. Mass.:
44863.39
Organism:
Mus musculus
Description:
ChEMBL_1280016
Residue:
399
Sequence:
MARRLQDELSAFFFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFVYEKGYQTSSGLISSVSVKLKGLAVTQLQGLGPQVWDVADYVFPAHGDSSFVVMTNFIMTPQQAQGHCAENPEGGICQDDSGCTPGKAERKAQGIRTGNCVPFNGTVKTCEIFGWCPVEVDDKIPSPALLHEAENFTLFIKNSISFPRFKVNRRNLVEEVNGTYMKKCLYHKILHPLCPVFSLGYVVRESGQDFRSLAEKGGVVGITIDWECDLDWHVRHCKPIYQFHGLYGEKNLSPGFNFRFARHFVQNGTNRRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKRHYYKQKKFKYAEDMGPGEGERDPAATSSTLGLQENMRTS
  
Inhibitor
Name:
BDBM50433071
Synonyms:
CHEMBL2376118
Type:
Small organic molecule
Emp. Form.:
C17H15N3O6
Mol. Mass.:
357.3175
SMILES:
Cc1nc(N=Nc2ccc(cc2)C(O)=O)c(CCC(O)=O)c(C=O)c1O |w:4.3|
Structure:
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