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Target
D-amino-acid oxidase
Ligand
BDBM50260723
Substrate
n/a
Meas. Tech.
ChEMBL_957137 (CHEMBL2378636)
Kd
26000±n/a nM
Citation
 Hopkins, SC; Heffernan, ML; Saraswat, LD; Bowen, CA; Melnick, L; Hardy, LW; Orsini, MA; Allen, MS; Koch, P; Spear, KL; Foglesong, RJ; Soukri, M; Chytil, M; Fang, QK; Jones, SW; Varney, MA; Panatier, A; Oliet, SH; Pollegioni, L; Piubelli, L; Molla, G; Nardini, M; Large, TH Structural, kinetic, and pharmacodynamic mechanisms of D-amino acid oxidase inhibition by small molecules. J Med Chem 56:3710-24 (2013) [PubMed]  Article 
Target
Name:
D-amino-acid oxidase
Synonyms:
D-Amino Acid Oxidase (DAAO) | D-amino-acid oxidase (DAAO) | DAMOX | DAO | OXDA_PIG
Type:
Flavoprotein
Mol. Mass.:
39338.01
Organism:
Sus scrofa (pig)
Description:
Homodimer.
Residue:
347
Sequence:
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTPFTTTDVAAGLWQPYTSEPSNPQEANWNQQTFNYLLSHIGSPNAANMGLTPVSGYNLFREAVPDPYWKDMVLGFRKLTPRELDMFPDYRYGWFNTSLILEGRKYLQWLTERLTERGVKFFLRKVESFEEVARGGADVIINCTGVWAGVLQPDPLLQPGRGQIIKVDAPWLKNFIITHDLERGIYNSPYIIPGLQAVTLGGTFQVGNWNEINNIQDHNTIWEGCCRLEPTLKDAKIVGEYTGFRPVRPQVRLEREQLRFGSSNTEVIHNYGHGGYGLTIHWGCALEVAKLFGKVLEERNLLTMPPSHL
  
Inhibitor
Name:
BDBM50260723
Synonyms:
1H-pyrrole-2-carboxylic acid | 2-pyrrolecarboxylic acid | CHEMBL509027 | PCA | pyrrole-2-carboxylic acid
Type:
Small organic molecule
Emp. Form.:
C5H5NO2
Mol. Mass.:
111.0987
SMILES:
OC(=O)c1ccc[nH]1
Structure:
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