Reaction Details Report a problem with these data
Target
G-protein coupled receptor 55
Ligand
BDBM50278379
Substrate
n/a
Meas. Tech.
ChEMBL_963381 (CHEMBL2388878)
IC50
6740±n/a nM
Citation
 Rempel, V; Volz, N; Gläser, F; Nieger, M; Bräse, S; Müller, CE Antagonists for the orphan G-protein-coupled receptor GPR55 based on a coumarin scaffold. J Med Chem 56:4798-810 (2013) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 55
Synonyms:
G protein-coupled receptor 55 | GPR55 | GPR55_HUMAN
Type:
PROTEIN
Mol. Mass.:
36649.72
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1292265
Residue:
319
Sequence:
MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
  
Inhibitor
Name:
BDBM50278379
Synonyms:
3-Benzyl-5-methoxy-7-methylchromen-2-one | CHEMBL470199
Type:
Small organic molecule
Emp. Form.:
C18H16O3
Mol. Mass.:
280.3178
SMILES:
COc1cc(C)cc2oc(=O)c(Cc3ccccc3)cc12
Structure:
Search PDB for entries with ligand similarity: