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Target
D(3) dopamine receptor
Ligand
BDBM50436543
Substrate
n/a
Meas. Tech.
ChEMBL_966818 (CHEMBL2400819)
Ki
0.430000±n/a nM
Citation
 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hübner, H; Gmeiner, P Functionally selective dopamine D2/D3 receptor agonists comprising an enyne moiety. J Med Chem 56:5130-41 (2013) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50436543
Synonyms:
CHEMBL2397480
Type:
Small organic molecule
Emp. Form.:
C24H30N2OS
Mol. Mass.:
394.573
SMILES:
CCCN(CCCCNC(=O)c1cc2ccccc2s1)[C@H]1CCC(=CC1)C#C |r,c:25|
Structure:
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