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Target
D(1A) dopamine receptor
Ligand
BDBM50436536
Substrate
n/a
Meas. Tech.
ChEMBL_966822 (CHEMBL2400823)
Ki
18000±n/a nM
Citation
 Hiller, C; Kling, RC; Heinemann, FW; Meyer, K; Hübner, H; Gmeiner, P Functionally selective dopamine D2/D3 receptor agonists comprising an enyne moiety. J Med Chem 56:5130-41 (2013) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DRD1 | DRD1_PIG | Dopamine D1 receptor
Type:
PROTEIN
Mol. Mass.:
49269.92
Organism:
Sus scrofa
Description:
ChEMBL_1460140
Residue:
446
Sequence:
MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50436536
Synonyms:
CHEMBL2397477
Type:
Small organic molecule
Emp. Form.:
C32H47N5O3
Mol. Mass.:
549.7473
SMILES:
CCCCn1ncc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2CCC(=CC2)C#C)n1 |r,c:35|
Structure:
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