Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50437190
Substrate
n/a
Meas. Tech.
ChEMBL_970296 (CHEMBL2403962)
EC50
2.6±n/a nM
Citation
 Paoletta, S; Tosh, DK; Finley, A; Gizewski, ET; Moss, SM; Gao, ZG; Auchampach, JA; Salvemini, D; Jacobson, KA Rational design of sulfonated A3 adenosine receptor-selective nucleosides as pharmacological tools to study chronic neuropathic pain. J Med Chem 56:5949-63 (2014) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3AR | Adenosine A3 receptor | AA3R_MOUSE | Adora3 | Gpcr2
Type:
PROTEIN
Mol. Mass.:
36460.91
Organism:
Mouse
Description:
ChEMBL_1515686
Residue:
319
Sequence:
MEADNTTETDWLNITYITMEAAIGLCAVVGNMLVIWVVKLNPTLRTTTVYFIVSLALADIAVGVLVIPLAIAVSLQVKMHFYACLFMSCVLLIFTHASIMSLLAIAVHRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKATLASSQNSSTLLCHFRSVVSLDYMVFFSFITWILVPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFDVKIPDVAMCLGILLSHANSMMNPIVYACKIKKFKETYFLILRAVRLCQTSDSLDSNMEQTTE
  
Inhibitor
Name:
BDBM50437190
Synonyms:
CHEMBL2401955
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: