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Target
Tissue alpha-L-fucosidase
Ligand
BDBM50240927
Substrate
n/a
Meas. Tech.
ChEMBL_974453 (CHEMBL2412525)
IC50
194000±n/a nM
Citation
 Martínez, RF; Araújo, N; Jenkinson, SF; Nakagawa, S; Kato, A; Fleet, GW (3R,4S,5R,6R,7S)-3,4,5,7-Tetrahydroxyconidine, an azetidine analogue of 6,7-diepicastanospermine and a conformationally constrained d-deoxyaltronojirimycin, from l-arabinose. Bioorg Med Chem 21:4813-9 (2013) [PubMed]  Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase 1 | FUCA1 | FUCO_BOVIN
Type:
PROTEIN
Mol. Mass.:
54093.12
Organism:
Bos taurus
Description:
ChEMBL_335897
Residue:
468
Sequence:
MRSWVVGARLLLLLQLVLVLGAVRLPPCTDPRHCTDPPRYTPDWPSLDSRPLPAWFDEAKFGVFVHWGVFSVPAWGSEWFWWHWQGEKLPQYESFMKENYPPDFSYADFGPRFTARFFNPDSWADLFKAAGAKYVVLTTKHHEGYTNWPSPVSWNWNSKDVGPHRDLVGELGTAIRKRNIRYGLYHSLLEWFHPLYLRDKKNGFKTQYFVNAKTMPELYDLVNRYKPDLIWSDGEWECPDTYWNSTDFLAWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCKDKFQPETLPDHKWEMCTSIDQRSWGYRRDMEMADITNESTIISELVQTVSLGGNYLLNVGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQSEKNSVWYTSKGLAVYAILLHWPEYGILSLISPIATSTTKVTMLGIQKDLKWSLNPSGKGLLVFLPQLPPAALPTEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50240927
Synonyms:
(2R,3R,4S,5R)-2-Hydroxymethyl-piperidine-3,4,5-triol | 1-deoxyaltronojirimycin | CHEMBL179347
Type:
Small organic molecule
Emp. Form.:
C6H13NO4
Mol. Mass.:
163.1717
SMILES:
OC[C@H]1NC[C@@H](O)[C@H](O)[C@@H]1O |r|
Structure:
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