Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50442755
Substrate
n/a
Meas. Tech.
ChEMBL_989366 (CHEMBL2443401)
Ki
7600±n/a nM
Citation
 Banerjee, A; Maschauer, S; Hübner, H; Gmeiner, P; Prante, O Click chemistry based synthesis of dopamine D4 selective receptor ligands for the selection of potential PET tracers. Bioorg Med Chem Lett 23:6079-82 (2013) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50442755
Synonyms:
CHEMBL2443001
Type:
Small organic molecule
Emp. Form.:
C22H34FN5O4
Mol. Mass.:
451.5349
SMILES:
COc1ccccc1N1CCN(Cc2cn(CCOCCOCCOCCF)nn2)CC1
Structure:
Search PDB for entries with ligand similarity: