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Target
Farnesyl diphosphate synthase
Ligand
BDBM50444842
Substrate
n/a
Meas. Tech.
ChEMBL_1282507 (CHEMBL3101060)
IC50
51±n/a nM
Citation
 Ferrer-Casal, M; Li, C; Galizzi, M; Stortz, CA; Szajnman, SH; Docampo, R; Moreno, SN; Rodriguez, JB New insights into molecular recognition of 1,1-bisphosphonic acids by farnesyl diphosphate synthase. Bioorg Med Chem 22:398-405 (2013) [PubMed]  Article 
Target
Name:
Farnesyl diphosphate synthase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
69493.18
Organism:
Toxoplasma gondii
Description:
ChEMBL_1282507
Residue:
646
Sequence:
MVDAVSLVSCRARHSHSLFAFSLSRRSCIQKHRFFSYVKSVPSSLPSPSSSSSPFTLSPRRRCLPPLVLPLEAAGHLPPALHSGSGISCPRSSSLSLSSSSPMRAPPSISLGLPPAQRPSLCFSPTSRLSAPVSPWSFSRQLSLATLAPLASVSSWKKAAALPKPDGAAAVSDERTSAERADALAGAWRASASHVEDRFKQAFPEVRGTLLSHIAGLDLPASLSARLLSYYARLLDYTCSGGKLTRGILVLYAAAAASHAPVLPPPSPSPAAAPASSASSVSSSPCSSSLAESERVPGSALSPALPPSSFRCLAALGWCVELLQSCFLVMDDVMDHSLTRRGKQCWYRCDGIGVSNAVNDSLVLEAAVYRVLREYLGDHPAYVQLQDLLLGNTFTTLIGQHLDSEDALAALSEASQNLESRQSEDNSSASSATAAGSSLLRDASLSDKDFTHHSYVSSSLSSSRSSPSLSASSLPSSEVLAQKLADRQATVARLKTSHYSFYLPTALGMTYGGLTDPALMAQAKELCLAIGEYFQVQDDYLDCFSDPKISGKIGSDIQEKKCCWLFVQAVRRASREDLAQLLRVYGQPEYVDWVKDLYRRLDLTSLYFQYEEETLAKLRRSVSSFPHDGMKAFFGLVLGRLHKRQK
  
Inhibitor
Name:
BDBM50444842
Synonyms:
CHEMBL3099278
Type:
Small organic molecule
Emp. Form.:
C8H21NO7P2
Mol. Mass.:
305.2024
SMILES:
CCCCCCNCC(O)(P(O)(O)=O)P(O)(O)=O
Structure:
Search PDB for entries with ligand similarity: