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Target
Delta carbonic anhydrase
Ligand
BDBM10872
Substrate
n/a
Meas. Tech.
ChEMBL_1282543 (CHEMBL3101210)
Ki
862±n/a nM
Citation
 Vullo, D; Del Prete, S; Osman, SM; De Luca, V; Scozzafava, A; Alothman, Z; Supuran, CT; Capasso, C Sulfonamide inhibition studies of thed-carbonic anhydrase from the diatom Thalassiosira weissflogii. Bioorg Med Chem Lett 24:275-9 (2013) [PubMed]  Article 
Target
Name:
Delta carbonic anhydrase
Synonyms:
ca1
Type:
PROTEIN
Mol. Mass.:
32261.40
Organism:
Thalassiosira weissflogii
Description:
ChEMBL_107983
Residue:
281
Sequence:
MEVDVVPNTKNYWQSSMCPVNVHWHLGTEHYSVGEYDENGSGPNGNVGVPYRRTLAEGEVQDGFRCHHYDPDDEAYTRPYEWKHCIGMEVGETYEVHWPHSGAGACGTTYQYQTPFYDGVFCNLDMETLQTLAPQDIANAVGVQGQIFTIVNDDTYYYPDLIRGWIVDEEMGMGQDIAMYTGSTTGESRSNEICSSYSPITWQVDRKCHKISASSFDKLCYDMKMQRDDMSDDLYAHGSRELVTPEYVANNQQTRRLTEKHEHNHSHGHSHVRGHQHHQWF
  
Inhibitor
Name:
BDBM10872
Synonyms:
4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-sulfonamide | CHEMBL7146 | aromatic/heteroaromatic sulfonamide 17
Type:
Small organic molecule
Emp. Form.:
C14H17N3O4S2
Mol. Mass.:
355.432
SMILES:
Nc1ccc(cc1)S(=O)(=O)NCCc1ccc(cc1)S(N)(=O)=O
Structure:
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