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Target
Delta carbonic anhydrase
Ligand
BDBM10880
Substrate
n/a
Meas. Tech.
ChEMBL_1282543 (CHEMBL3101210)
Ki
83±n/a nM
Citation
 Vullo, D; Del Prete, S; Osman, SM; De Luca, V; Scozzafava, A; Alothman, Z; Supuran, CT; Capasso, C Sulfonamide inhibition studies of thed-carbonic anhydrase from the diatom Thalassiosira weissflogii. Bioorg Med Chem Lett 24:275-9 (2013) [PubMed]  Article 
Target
Name:
Delta carbonic anhydrase
Synonyms:
ca1
Type:
PROTEIN
Mol. Mass.:
32261.40
Organism:
Thalassiosira weissflogii
Description:
ChEMBL_107983
Residue:
281
Sequence:
MEVDVVPNTKNYWQSSMCPVNVHWHLGTEHYSVGEYDENGSGPNGNVGVPYRRTLAEGEVQDGFRCHHYDPDDEAYTRPYEWKHCIGMEVGETYEVHWPHSGAGACGTTYQYQTPFYDGVFCNLDMETLQTLAPQDIANAVGVQGQIFTIVNDDTYYYPDLIRGWIVDEEMGMGQDIAMYTGSTTGESRSNEICSSYSPITWQVDRKCHKISASSFDKLCYDMKMQRDDMSDDLYAHGSRELVTPEYVANNQQTRRLTEKHEHNHSHGHSHVRGHQHHQWF
  
Inhibitor
Name:
BDBM10880
Synonyms:
AZA | AZA2 | AZM acetazolamide | Acerazolamide, AAZ | Acetazolamide | Acetazolamide (AAZ) | Acetazolamide (AZA) | Acetazolamide (AZM) | Acetazolamide, 5 | Acetazolamide, AAZ | Acetazolamide, AZA | Acetazolamide, AZM | CHEMBL20 | N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide | Sulfonamide, 1 | US10172837, Acetazolamide | US11278534, Example acetazolamide | US11535599, Example acetazolamide | sulfonamide 1
Type:
Small organic molecule
Emp. Form.:
C4H6N4O3S2
Mol. Mass.:
222.245
SMILES:
CC(=O)Nc1nnc(s1)S(N)(=O)=O
Structure:
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