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Target
Adenosine deaminase
Ligand
BDBM50004697
Substrate
n/a
Meas. Tech.
ChEMBL_907754 (CHEMBL3065677)
IC50
5000±n/a nM
Citation
 Lindell, SD; Moloney, BA; Hewitt, BD; Earnshaw, CG; Dudfield, PJ; Dancer, JE The design and synthesis of inhibitors of adenosine 5'-monophosphate deaminase. Bioorg Med Chem Lett 9:1985-90 (1999) [PubMed]  Article 
Target
Name:
Adenosine deaminase
Synonyms:
ADA | ADA_BOVIN | Adenosine aminohydrolase
Type:
Enzyme
Mol. Mass.:
40910.44
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
363
Sequence:
MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPEFLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAIDLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGYHTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIFKSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAEQCL
  
Inhibitor
Name:
BDBM50004697
Synonyms:
DEAMINOFORMYCIN
Type:
Small organic molecule
Emp. Form.:
C10H12N4O4
Mol. Mass.:
252.2267
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1n[nH]c2cncnc12
Structure:
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